Stephen Devoto is the man. This is a question on the Developmental Bio practice exam:
(I know some of you are going, EW! SCIENCE WORDS! But just read this. It’s short.)
In another new species (in the administriensis family of worms), cells of the heart and the gut contain similar levels of processed doug1 mRNA, but the steady state level of the Doug1 protein is 10 times higher in the heart than in gut. Propose a control mechanism that could be responsible for this difference.
I find a mutant strain of this worm that has equal amounts of Doug1 protein in heart and gut. The mutant gene, which I name midge1, binds tightly to the doug1 mRNA. Propose a mechanism for how Midge1 controls Doug1.