Cool sorta-relevant science tidbit

Live from the basement of Sci Li– It’s neuropharmacology!


PCP (phencyclidine) and ketamine are noncompetitive NMDA receptor antagonists whose effects mimic some of the symptoms of schitzophrenia. PCP has been described to me as LSD’s evil psychotic twin. Ethanol/ethyl alchol is b33r.


“At higher doses, these drugs are disassociative anesthetics. Many are used predominantly in veterinary practice; however, ketamine has been used successfully as a pediatric anesthetic because children are less likely than adults to exhibit psychotic-like side effects. Interestingly, doses of ethanol associated with the upper range of intoxication in humans exert effects on NMDA receptors that are similar to those produced by phencyclidine and related drugs.

Keep that in mind the next time you set out to get wasted.

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